Ọrịa anụmanụ: Ọgaụ na Nrụpụta Avian

News 01

Nchọpụta nke mbụ nke H4N6 Sublian na-efe efe nke oria avian na Mallard ducks (Anas playrhynchos) n'Izrel

Avushai, Irina Shkoda, Luba Simanov, Gigal Carnoush, Panine M gameth, Ruri CK Bill Bowie, Ran Netan

PMID: 35687561; DII: 10.1111 / tbed.14610

Nje Virus Avian (AIv) na-eme nnukwu ihe iyi egwu anụmanụ na ahụike mmadụ n'ụwa niile. Ka mmiri na-ebugharị Aiv n'ụwa niile, na-enyocha ihu na oke ọhịa na-abawanye na ọrịa ọrịa na ụmụ anụmanụ na ụmụ anụmanụ. N'ime omumu a, Odide H4N6 Aiv Aiv E kewapụrụ na nke izizi site na Faecal samps ducks (Anas Playrhynchos) n'Izrel. Nsonaazụ phylogenetic nke ha na mkpụrụ ndụ mkpụrụ osisi na-egosi na nsogbu a nwere njikọ chiri anya na Europe na Asia na Asia. Dika Israel di n'akuku uzo Arsctic-Africa, a na-eche na udiri nnụnụ na-ebubata ya. Nyocha nke mkpụrụ ndụ nke mkpụrụ ndụ (PB1, PB2, PB2, PB, M na NS), na-egosi na ihe omume mweghachi gara aga mere na nke a. Nke a H4N6 Subturpe nke AIV nwere ọnụego mgbapụta dị elu, nwere ike ibute ezì dị elu ma nwee ike igbu mmadụ, ma nwee ike ibute ọrịa Zoonotic n'ọdịnihu.

News 02

Isi nke oria avian na EU, Machị-June 2022

Onye ikike nchekwa European, Center Center maka Mgbochi Ọrịa na Njikwa Ọrịa, ụlọ akwụkwọ iwu European Union Relicenza

PMID: 35949938; PMCID: PMC935671; DII: 10.2903 / J.EFSA.2022.740

Na 2021-2022, nnukwu nje vinentenic (hpai) bụ ọrịa na-efe efe kachasị njọ na Europe, ndị nwere puku mmadụ iri abụọ na asatọ na Europe na-ebute nde iri anọ na isii. N'agbata 16 Machị na 10 June 2022, ngụkọta nke 28 EUEA / ea na-enwekarị ọrịa nje na-efe efe (HPAIV), na-ahụ maka anụ ọhịa (ikpe 22). N'ime oge a na-enyocha, 86% nke ọkụkọ ọkụkọ bụ n'ihi nnyefe HPAIV, yana France na-akwụ ụgwọ maka 24% na mba ndị ọzọ metụtara ihe na-erughị 2%. Germany nwere ọnụ ọgụgụ kachasị elu na nnụnụ anụ ọhịa (158 okwu), nke Netherlands (ikpe 98) na UK (48 okwu).

Nsonaazụ nke nyocha nke mkpụrụ ndụ ihe nketa na-egosi na Hpaiv na-egbu oge ugbu a sitere na ụdị dị iche iche 2.3.4 B. Ebe ọ bụ na akụkọ ikpeazụ, anọ H5N6, ọrịa H9N2 na abụọ na abụọ na China na China na otu H5N1 mmadụ na-akọworị na USA. A na-enyocha ihe ize ndụ nke ọrịa na-efe efe dị ka ọnụ ọgụgụ mmadụ na ala na-agafeghị oke maka ndị bi na EU / EEA.

 News 03

Mmụba na ibibi 127, 183 na 212 na ha Gene na-emetụta

Antigenicity, na-emegharị ya na pamụ aka nke H9N2 na-efe efe virus

MenGlu fan,Bing liang,Yongzhen Zhao,Yap Zhang,Qinzheng liu,Miao Tian,Yiqing Zheng,Huzhi Xia,Yasuo suzuki,Hulan Chen,Jichiei ping

PMID: 34724348; DII: 10.1111 / tbed.14363

Ibi ụzọ H9N2 nke nje oria avian (AIv) bụ otu n'ime ikike ndị isi na-emetụta ahụike nke ụlọ ọrụ ọkụkọ. N'ime ọmụmụ a, ụdị abụọ nke Suntype AIV nwere ụdị mkpụrụ ndụ ihe nketa a, nke a na-akpọ / JS / JS / JS / JS / JS / JS / JS / JS / JS / JS / JS / JS / JS / JS / JS / JS / JS / JS / JS / JS / JS / JS / JS / JS / JS / JS / JS / JS / JS / JS / JS / JS). Nyocha nyocha gosipụtara na JS / 76 dị iche na mpaghara atọ acid atọ (127, 183 na 212) nke Haemaglutnun (ha). Iji nyochaa ọdịiche dị na ihe dị n'etiti JS / 75 na JS / 76, nke isii na-akwụghachi ụgwọ site na iji usoro nke mkpụrụ ndụ ya na-eme / 8/84 (pr8) dị ka isi yinye. Data site na nnwale ọkụkọ na nnwale ndị gosiri na R-76 / pr8 gosipụtara na mgbapụ antigenic nke Amino acid na ọnọdụ 127 na 183 na Ha Gene. Ọmụmụ ihe ndị ọzọ gosipụtara na glycosyyyyylation na 127N saiti mere na JS / 76 na ụmụ ya. Receator na-eme ka ihe ngosi niile gosipụtara na nje virus niile, ma e wezụga 127n glycosation-ezughi oke, ngwa ngwa na ndị na-anabata ya. Ulo Kinetics na òké na-eme ka ọ bụrụ nje virus nke 127N-glycostylated revices na mkpụrụ ndụ A549 na-adịchaghị mma na ụmụ oke. N'ihi ya, glycosyylation na uto amino na-arịa ọrịa a na-arụ ọrụ maka ọdịiche dị na antigenicy na pamụaka nke ụdị 2 H9N2.

Isi Iyi: China Anụmanụ Anụmanụ na Center Epidemiology